Seetaram Mohaptra

Dr. Mohapatra obtained his M.Sc from Berhampur University, Berhampur (1999) and M.Phil from same University in 2001. Then he did Ph.D from NCL, Pune under the supervision of Dr. Mukund Gurjar in 2008. His postdoctoral work at University of Southwestern Medical Research Center, Dallas, Texas, USA consisted of medicinal chemistry research (2008-2009). He further continued his postdoctoral research in Albert Einstein College of Medicine, USA (2009-2010).From may 2011 onwards, he had been associated with Ravenshaw University. The focus of Mohapatra’s group include small molecule synthesis by employing new catalytic reactions with focus on stereoselective transformation with unique structural features and biological properties.

Selected Publications

1. Mishra, M.; Mishra, N. P.; Raiguru, B. P.; Das, T.; Mohapatra, S.; Nayak, S.; Mishra, D. R.; Panda, J.; Sahoo, D.K, ChemistrySelect, 2021, 6, 3570-3575.
2. Mishra, N. P.; Satish. L.; Mohapatra, S.; Panda, P.; Nayak, S. Research on chemical intermediates, 2021, 47, 1181–1195.
3. Baral, N.; Mishra, D. R.; Mishra, N. P.; Mohapatra, S.; Raiguru, B. P.; Panda, P.; Nayak, S.; Nayak, M.; Kumar, P. S. Journal of Heterocyclic Chemistry, 2020,57, 575-589.
4. Mishra, M.; Mohapatra, S.; Mishra, N. P.; Jena, B. K.; Panda, P.; Nayak, S. Tetrahedron Letters, 2019, 60, 150925.
5. Falck, J.R.; Koduru, S.R.; Mohapatra, S.;Manne, R.; Atcha, K.R.; Manthati, V.L.; Capdevila, J.H.; Christian, S.; Imig, J.D.; Campbell, W.B. Journal of Medicinal Chemistry, 2014, 57, 6887-7144.

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About

Academics

Dr. Seetaram Mohapatra’s Group

1. Mitali Mishra

Education: M.Phil.(North Odisha University, 2010)

M.Sc Chemistry (F. M University, 2006)

B.Sc. Chemistry (Utkal University, 2004)

Role: Teacher fellow

Research Project: Fe(III)Cl3 catalysed reaction for the synthesis of heterocyclic.

Email-id: mitalimishra94@gmail.com

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2. Nilima Priyadarsini Mishra

Education: M.Sc Chemistry ( Berhampur University,2015)

B.Sc. Chemistry(Utkal University, 2013)

Role: DST INSPIRE fellow         

Research Project: Synthesis, bioactivity of 2H-chromene based functionalized molecules and inclusion complex of nitrochromene with β-CD.

Email-id: sumali252@gmail.com

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3. Bishnu Prasad Raiguru

Education: M.Sc Chemistry ( Ravenshaw University,2016)

B.Sc. Chemistry (Utkal University, Cuttack, 2014)

Role: (DRDO SRF fellow)          

Research Project:Design and synthesis of flavones-stilbene based hybrid natural products as potential antimalarial drug.

Email-id: bishnuprasadtuna@gmail.com

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4. Tapaswini Das

Education: M.Sc Chemistry ( Ravenshaw University,2017)

B.Sc. Chemistry (Ravenshaw University, Cuttack, 2015)

Role: (DST INSPIRE JRF fellow)

Research Project: Synthesis of chromene based pyrazoles using Michael addition reaction and its biological studies.

Email-id : dastapaswini70@gmail.com

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5. Naresh Kumar Rauta

Education: M.Sc Chemistry ( OUAT, Odisha, 2019)

B.Sc. Chemistry (Utkal University, Cuttack, 2015)

Role: M.Phil. Scholar

Research Project: Synthesis of chromene functionalized molecules  using Michael addition reaction .

Email-id : bablu001dhero@gmail.com

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ALUMNI GROUP

1. Sujitlal Bhakta

Ph.D. Awarded: 2017

Current Position: Research Associate (Biochemistry), Anthropological Survey of India, Ministry of Culture, Govt. of India.

Email.id: bhaktasujitlal89@gmail.com

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2. Priyabrata Pattanaik

Ph.D. Awarded: 2019

Current Position: Assistant Professor in Govt. Auto college, Phulbani.

Email.id: priyabrata.pattanaik797@gmail.com

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3. Nilofar Baral

Ph.D. Awarded: 2020

Current Position: Lecturer in Kamakhyanagar College, Kamakhyanagar.

Email. Id: nilofarbaral@gmail.com

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M.Phil.

  1. Priyanka Sahoo-2012 (Punjab National Bank, Cuttack)
  2. M. Saranya-2013 (Assistant Scientific Officer, DSSL, Puri)
  3. Dilip Kumar Subudhi- 2016 (Assistant Scientific Officer, DSSL, Cuttack)
  4. Soham Panda-2016 (Ph.D., USA)
  5. Sourav Dey-2018 (Lecturer at Raghunath Jew College, Cuttack)
  6. S.K Sakir-2018 (PGT at Delhi Public School, Paradeep )Sidharth Sankar Panda-2019 (

Research

  1. Catalytic Reaction
  2. Medicinal Chemistry
  3. Natural Product Synthesis
  4. Carbohydrate Chemistry

Our group is interested in four general areas of research. We develop new catalytic reactions with focus on stereoselective transformation. We synthesize small molecules with unique structural features and biological properties. We integrate our work into medicinal chemistry collaborations with laboratories like IICT-Hyderabad, SOA University, KIIT University, DRDE Gwalior and ICGEB, New Delhi.

1. Organocatalyzed Michael addition Reaction to the α, β- unsaturated nitroolefin
Seetaram Mohapatra 1
2. FeCl3 Catalyzed reaction to the synthesis of heterocyclic compound:
Seetaram Mohapatra 2

Completed Research project:

 

  • CSIR Project: 2014-2017
  1. Project Title: Design and synthesis of chromene-coumarin based hybrid natural Product as anticancer agent.
  • DST Project: 2013-2016
  1. Project Title: Design and Synthesis of Novel Flavone based DPP4 inhibitor.
  • UGC Project: 2015
  1. Project Title: Design and synthesis of hybrid compounds.
  • UGC Project: 2012-2014
  1. Project Title: Design and Synthesis of Boron containing–flavone used as antidiabetic  agent

Current Research Project:

  • DRDO Project: 2017-2021
  1. Project Title: Design and synthesis of flavone-stilbene based hybrid natural products as potent antimalarial agent.
  • CSIR Project: 2019-2022
  1. Project Title: Design and synthesis of chromene based 1,2,4-oxadiazole derivatives as pfkb3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3) inhibitor.
  • DRDO,LSRB Project: 2021-2024
  1. Project Title: Design, synthesis and evaluation of sugarconjugated pyridine oximes as reactivators of organophosphorous nerve agent inhibited acetylcholinesterase.

Publications

  1. Mishra, M.; Mishra, N. P.; Raiguru, B. P.; Das, T.; Mohapatra, S.; Nayak, S.; Mishra, D. R.; Panda, J.; Sahoo, D.K, ChemistrySelect, 2021, (Accepted). 
  2. Das, T.; Mohapatra, S.; Mishra, N. P.; Nayak, S.; Raiguru, B. P. ChemistrySelect, 2021, (Accepted). 
  3. Mishra, D. R.; Nayak, S.; Raiguru, B. P.; Mohapatra, S.; Podh, M. B. Sahoo, C. R.; Padhy R. N. Journal of Heterocyclic Chemistry, 2021, 58, 111-126. 
  4. Mishra, N. P.; Satish. L.; Mohapatra, S.; Panda, P.; Nayak, S. Research on chemical intermediates, 2021, 47, 1181–1195.
  5. Raiguru, B. P.; Nayak, S.; Mishra, D. R.; Das, T.; Mohapatra, S.; Mishra, N. P. Asian Journal of Organic Chemistry, 2020, 9, 1088-1132.
  6. Baral, N.; Mishra, D. R.; Mishra, N. P.; Mohapatra, S.; Raiguru, B. P.; Panda, P.;  Nayak, S.; Nayak, M.;  Kumar, P. S. Journal of Heterocyclic Chemistry, 2020,57, 575-589.
  7. Mishra, M.; Mohapatra, S.; Mishra, N. P.; Jena, B. K.; Panda, P.; Nayak, S. Tetrahedron Letters, 2019, 60, 150925.
  8. Baral, N.; Mohapatra, S.; Raiguru, B. P.; Mishra, N. P.; Panda, P.; Nayak, S.; Pandey,S. K.; Kumar, P. S.; Sahoo, C. R. Journal of Heterocyclic Chemistry, 2019, 56,552-565.
  9. Nayak, S.; Panda, P.; Raiguru, B. P.; Mohapatra, S.; Purohit,C. S. Org. Biomol. Chem., 2019,17,74-82.
  10. Nayak, S.; Panda, P.; Mohapatra, S.; Raiguru, B. P.; Baral, N, Journal of Heterocyclic Chemistry, 2019, 56,1757-1770.
  11. Nayak, S.; Pattanaik, P.; Mohapatra, S.; Mishra, D. R.; Panda, P.; Raiguru, B. P.; Mishra,N. P.; Jena, S.; Biswal, H. S. Synthetic Communications, 2019, 49, 1823-1835.
  12. Mishra, N. P.; Mohapatra, S.; Panda, P.; Nayak, S. Current Organic Chemistry, 2018, 22, 1959-1985.
  13. Pattnaik,P.; Nayak, S.; Mishra,D. R.; Panda, P.; Raiguru, B. P.; Mishra,N. P.; Mohapatra, S.; Mallapudi, N. A.; Purohit, C. S. Tetrahedron Letters,2018,59,2688-2694.
  14. Panda, P.; Nayak, S.; Sahoo, S. K.; Mohapatra, S.; Nayak, D.; Pradhan, R.; Kundu, C. N. RSCAdvances, 2018, 8,16802-16814.
  15. Panda, P.; Nayak, S.; Bhakta, S.; Mohapatra, S.; Murthy, T. R. J. Chem. Sci., 2018, 130, 127-142.
  16. Mohapatra, S.; Baral, N.; Mishra, N. P.; Panda, P.; Nayak, S. Open Chemistry Journal, 2018, 5, 18-31.
  17. Baral, N.; Nayak, S.; Pal, S.; Mohapatra, S.; IUCrData 3(1), DOI: 10.1107/S2414314618001293.
  18. Nayak, S.; Panda, P.; Bhakta, S.; Mishra, S. K.; Mohapatra, S. RSC Adv., 2016, 6, 96154-96175.
  19. Nayak, S.; Chakroborty, S.; Bhakta, S.; Panda, P.; Mohapatra, S. Research on Chemical Intermediates, 2016, 42, 2731-2747.
  20. Nayak, S.; Mishra, S. K.; Bhakta, S.; Panda, P.; Baral, N.; Mohapatra, S.; Purohit, C. S.; Satha, P. Letters in Organic Chemistry, 2016, 13(1), 11–21.
  21. Nayak, S.; Chakroborty, S.; Bhakta, S.; Panda, P.; Mohapatra, S.; Kumar, S.; Jena, P. K.; Purohit, C. S. Letters in Organic Chemistry, 2015, 12(1), 352-358.
  22. Mohapatra, S.; Bhakta, S.; Baral, N.; Nayak,S. Research on Chemical Intermediates, 2015, 41, 4545-4553.
  23. Mohapatra, S.; Bhakta, S.; Chakroborty, S.; Tripathy, M.;  Nayak, S. Research on Chemical Intermediates, 2014, 41(10), 7799–7813. doi:10.1007/s11164-014-1860-x.
  24. Falck, J.R.; Koduru, S.R.; Mohapatra, S.;Manne, R.; Atcha, K.R.; Manthati, V.L.; Capdevila, J.H.; Christian, S.; Imig, J.D.; Campbell, W.B. Journal of Medicinal Chemistry, 2014, 57, 6887-7144.
  25. Mohapatra, S.; Bhanja, C.; Jena. S.; Chakraborty,S.; Nayak, S., Research on Chemical Intermediates, 2013, 39, 1459-1462.
  26. Mohapatra, S.; Bhanja, C.; Jena. S.; Chakraborty,S.; Nayak, S., Synthetic Communication, 2013,43,1993-2007.
  27. Mohapatra, S.; Nayak, S., Mishra, S. K.; Pattanaik, P. Letters in Organic Chemistry, 2013, 10, 65-69.
  28. Bhanja, C.; Jena. S.; Nayak, S.; Mohapatra, S., Beilstein Journal of Organic Chemistry, 2012, 8,1668-1694.
  29. Das, B. C.; Tang, X.-Y.; Sanyal, S.; Mohapatra, S.; Rogler, P.; Nayak, S.; Evans, T. Tetrahedron Letters, 2011, 52(19), 2433–2435. doi:10.1016/j.tetlet.2011.03.011.
  30. Mohapatra D.K.; Naidu P.R.; Reddy, D.S.; Nayak.;Mohapatra, S.; E. Journal of Organic Chemistry 2010, 6263-6268. 
  31. Das, B.C.; Mohapatra S.; Campbell P.D.; Nayak, S.; Mahalingam, S.M,; Evans T. Tetrahedron Lett. 2010, 51, 2567-2570.
  32. Mohapatra D. K.; Nayak S.; Mohapatra S.; Chorghade M.S.; Gurjar M. K Tetrahedron Lett. 2007, 48,5197- 5200. 
  33. Mohapatra D. K.; Mohapatra S.; Gurjar M. K. Tetrahedron Lett.2006, 47, 5943–5947. 
  34. Gurjar, M. K.; Mohapatra S; Phalgune U. D.; Puranik V. G.; Mohapatra D. K. Tetrahedron Lett.2004, 45, 7899–7902.

Teaching

  • Natural Product Synthesis.
  • Carbohydrate Chemistry.
  •  Heterocyclic Chemistry.
  • Disconnection Approach.
  • Structural Elucidation of Organic Compounds.